Substance / Medication

Procaine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Substance withdrawal syndrome

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:

[Effect of dexamethasone combined with oxybuprocaine hydrochloride gel on prevention of postoperative sore throat after nasal endoscopy].

Shi C M, Wang X D, Liu Y K et al. · Beijing Da Xue Xue Bao Yi Xue Ban · 2022

PMID: 35435194RCTFull text (PMC)

Efficacy and Safety of Oxybuprocaine Hydrochloride Gel in Alleviating Pain during Male Urethral Catheterization: A Single-Center Randomized Controlled Study.

Dong Zhenkun, Qu Xutong, Zhang Lu et al. · Int J Clin Pract · 2022

PMID: 36177365RCTFull text (PMC)

Changes in central corneal thickness values after instillation of oxybuprocaine hydrochloride 0.4%.

Ogbuehi Kelechi C, Chijuka John C, Osuagwu Uchechukwu L · Cont Lens Anterior Eye · 2012

PMID: 22704944RCT

Triamcinolone acetonide vs procaine hydrochloride injection in the management of carpal tunnel syndrome: randomized placebo-controlled study.

Karadaş Ömer, Tok Fatih, Akarsu Selim et al. · J Rehabil Med · 2012

PMID: 22674243RCT

Plasma concentration and local anesthetic activity of procaine hydrochloride following subcutaneous administration to horses.

Kuchembuck Natasha L, Colahan Patrick T, Zientek Keith D et al. · Am J Vet Res · 2007

PMID: 17472448RCT

Degree of corneal anaesthesia after topical application of 0.4% oxybuprocaine hydrochloride and 0.5% proparacaine hydrochloride ophthalmic solution in clinically normal cattle.

Little W B, Jean G St, Sithole F et al. · Aust Vet J · 2016

PMID: 27237118Observational

Cognitive deficit in first-time coronary artery bypass graft patients: a randomized clinical trial of lidocaine versus procaine hydrochloride.

Ghafari R, Baradari A Gholipour, Firouzian A et al. · Perfusion · 2012

PMID: 22588946Observational

The effectiveness of triamcinolone acetonide vs. procaine hydrochloride injection in the management of carpal tunnel syndrome: a double-blind randomized clinical trial.

Karadaş Omer, Tok Fatih, Ulaş Umit Hidir et al. · Am J Phys Med Rehabil · 2011

PMID: 21273900Observational

Pharmacokinetics of penicillin G procaine versus penicillin G potassium and procaine hydrochloride in horses.

Uboh C E, Soma L R, Luo Y et al. · Am J Vet Res · 2000

PMID: 10895905Observational

Successful Dental Treatments Using Procaine Hydrochloride in a Patient Afraid of Local Anesthesia but Consenting for Allergic Testing with Lidocaine: A Case Report.

Ayuse Terumi, Kurata Shinji, Ayuse Takao · Local Reg Anesth · 2020

PMID: 32903881Case ReportFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Procaine hydrochloride (substance)
SNOMED CT: 73444000
UMLS CUI: C0358490

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.