Substance / Medication

Promethazine

Overview

Active Ingredient
promethazine
RxNorm CUI
8745

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

71 trials linked to this intervention

71
Total Trials
9
Recruiting
23
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Haloperidol plus promethazine for psychosis-induced aggression.
Huf Gisele, Alexander Jacob, Gandhi Pinky et al. · Cochrane Database Syst Rev · 2016
PMID: 27885664Meta-AnalysisFull text (PMC)
[Haloperidol plus promethazine for agitated patients--a systematic review].
Huf Gisele, Coutinho Evandro Silva Freire, Adams Clive Elliot · Braz J Psychiatry · 2009
PMID: 19784494Meta-Analysis
Haloperidol plus promethazine for psychosis-induced aggression.
Huf Gisele, Alexander Jacob, Allen Michael H et al. · Cochrane Database Syst Rev · 2009
PMID: 19588366Meta-Analysis
Haloperidol plus promethazine for psychosis induced aggression.
Huf G, Alexander J, Allen M H · Cochrane Database Syst Rev · 2005
PMID: 15654706Meta-Analysis
Promethazine Effects on Motion Sickness During Altered Gravity Induced by Parabolic Flight.
Abbott Renee, Weinrich Madison M, Keller Nathan W et al. · Aerosp Med Hum Perform · 2025
PMID: 41253367RCT
Effectiveness of promethazine on preoperative and intraoperative sequelae in cleft palate surgeries.
Vedha Vivigdha A, Senthil Murugan P, Santhosh Kumar M P et al. · Orthod Craniofac Res · 2024
PMID: 38265116RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Promethazine (substance)
SNOMED CT
372871004
UMLS CUI
C0033405
RxNorm CUI
8745

Clinical Data

This intervention maps to 7 entities in the Ltrl knowledge graph.

7
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
71
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.

Promethazine — Conditions, Biomarkers & Specialists | Ltrl | Healos