Strategies in Maintenance for Patients Receiving Long-term Therapy (S.I.M.P.L.E.) With MMX (Multi-Matrix System) Mesalamine for Ulcerative Colitis (UC)

NCT00446849Phase 4Completed290 enrolled

View all 84 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

The effect of psyllium consumption on anthropometric indices: a systematic review and dose-response meta-analysis of randomized controlled trials.

Gholami Zeinab, Paknahad Zamzam · J Health Popul Nutr · 2025

PMID: 41126340Meta-AnalysisFull text (PMC)

The effect of psyllium on fasting blood sugar, HbA1c, HOMA IR, and insulin control: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials.

Gholami Zeinab, Clark Cain C T, Paknahad Zamzam · BMC Endocr Disord · 2024

PMID: 38844885Meta-AnalysisFull text (PMC)

Psyllium is a natural nonfermented gel-forming fiber that is effective for weight loss: A comprehensive review and meta-analysis.

Gibb Roger D, Sloan Kyle J, McRorie Johnson W · J Am Assoc Nurse Pract · 2023

PMID: 37163454Meta-AnalysisFull text (PMC)

The effect of psyllium consumption on weight, body mass index, lipid profile, and glucose metabolism in diabetic patients: A systematic review and dose-response meta-analysis of randomized controlled trials.

Xiao Zhifang, Chen Hui, Zhang Yu et al. · Phytother Res · 2020

PMID: 31919936Meta-Analysis

The effect of psyllium supplementation on blood pressure: a systematic review and meta-analysis of randomized controlled trials.

Clark Cain C T, Salek Mina, Aghabagheri Elahe et al. · Korean J Intern Med · 2020

PMID: 32066221Meta-AnalysisFull text (PMC)

The effects of psyllium supplementation on body weight, body mass index and waist circumference in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.

Darooghegi Mofrad Manije, Mozaffari Hadis, Mousavi Seyed Mohammad et al. · Crit Rev Food Sci Nutr · 2020

PMID: 30880409Meta-Analysis

Effect of psyllium (Plantago ovata) fiber on LDL cholesterol and alternative lipid targets, non-HDL cholesterol and apolipoprotein B: a systematic review and meta-analysis of randomized controlled trials.

Jovanovski Elena, Yashpal Shahen, Komishon Allison et al. · Am J Clin Nutr · 2018

PMID: 30239559Meta-Analysis

Meta-Analysis of Usefulness of Psyllium Fiber as Adjuvant Antilipid Therapy to Enhance Cholesterol Lowering Efficacy of Statins.

Brum Jose, Ramsey David, McRorie Johnson et al. · Am J Cardiol · 2018

PMID: 30078477Meta-Analysis

Psyllium fiber improves glycemic control proportional to loss of glycemic control: a meta-analysis of data in euglycemic subjects, patients at risk of type 2 diabetes mellitus, and patients being treated for type 2 diabetes mellitus.

Gibb Roger D, McRorie Johnson W, Russell Darrell A et al. · Am J Clin Nutr · 2015

PMID: 26561625Meta-Analysis

The role of psyllium fibre supplementation in treating irritable bowel syndrome.

Chouinard Laura E · Can J Diet Pract Res · 2011

PMID: 21382232Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Internal Medicine Physician

Internal Medicine

NUCC 207R00000X

Gastroenterology Physician

Internal Medicine — Gastroenterology

NUCC 207RG0100X

Find a Provider

Health Goals

Goals connected through associated conditions

Improve Gut Health

Quick Facts

Type: Substance / Medication
Fully Specified Name: Psyllium (substance)
SNOMED CT: 52370008
UMLS CUI: C0033979
RxNorm CUI: 8928

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.