Substance / Medication

Quinacrine

Overview

Active Ingredient
quinacrine
RxNorm CUI
9061

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Quinacrine treatment trial for sporadic Creutzfeldt-Jakob disease.
Geschwind Michael D, Kuo Amy L, Wong Katherine S et al. · Neurology · 2013
PMID: 24122181RCTFull text (PMC)
Efficacy and Tolerability of Quinacrine Monotherapy and Albendazole Plus Chloroquine Combination Therapy in Nitroimidazole-Refractory Giardiasis: A TropNet Study.
Neumayr Andreas, Schunk Mirjam, Theunissen Caroline et al. · Clin Infect Dis · 2021
PMID: 34115100Observational
Comparative and Mechanistic Study on the Anticancer Activity of Quinacrine-Based Silver and Gold Hybrid Nanoparticles in Head and Neck Cancer.
Hembram Krushna Chandra, Chatterjee Subhajit, Sethy Chinmayee et al. · Mol Pharm · 2019
PMID: 31145852Observational
Long-term risk of hysterectomy and ectopic pregnancy among Vietnamese women using the quinacrine hydrochloride pellet system vs. intrauterine devices or tubal ligation for contraception.
Jones Judith K, Tave Arlene, Pezzullo John C et al. · Eur J Contracept Reprod Health Care · 2018
PMID: 29683010Observational
The quinacrine experience in a population of patients with cutaneous lupus erythematosus and dermatomyositis.
Mittal Lavanya, Werth Victoria P · J Am Acad Dermatol · 2017
PMID: 28711090ObservationalFull text (PMC)
The Use of Quinacrine in Nitroimidazole-resistant Giardia Duodenalis: An Old Drug for an Emerging Problem.
Requena-Méndez Ana, Goñi Pilar, Rubio Encarnación et al. · J Infect Dis · 2017
PMID: 28453841Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Mepacrine (substance)
SNOMED CT
387445007
UMLS CUI
C0034403
RxNorm CUI
9061

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.