Substance / Medication

Recombinant urate oxidase

Overview

Active Ingredient
rasburicase
RxNorm CUI
283821

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Enhancing recombinant urate oxidase stability and catalytic function with TMAO osmolyte: integrated experimental and computational approaches.
Shahba Samira, Zaboli Maryam, Shaebani Ali Akbar et al. · J Biomol Struct Dyn · 2025
PMID: 41138279Other
Fixed-Dose Recombinant Urate Oxidase in the Treatment of Paediatric Tumour Lysis Syndrome: A Regional Cancer Centre Experience.
L Appaji, Reddy Jyothi M, Chebbi Pooja Gujjal et al. · Asian Pac J Cancer Prev · 2021
PMID: 34967569OtherFull text (PMC)
Arxula adeninivorans recombinant urate oxidase and its application in the production of food with low uric acid content.
Trautwein-Schult Anke, Jankowska Dagmara, Cordes Arno et al. · J Mol Microbiol Biotechnol · 2013
PMID: 24022585Other

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Recombinant urate oxidase (substance)
SNOMED CT
415249009
UMLS CUI
C0937932
RxNorm CUI
283821

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.