Substance / Medication

Revefenacin

Overview

Active Ingredient
revefenacin
RxNorm CUI
2102775

Indications

YUPELRI is indicated for the maintenance treatment of patients with chronic obstructive pulmonary disease (COPD).

Labeler: Viatris Specialty LLCUpdated: 2022-05-03T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

YUPELRI is contraindicated in patients with hypersensitivity to revefenacin or any component of this product.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Revefenacin Area Under the Curve Spirometry in Patients with Moderate to Very Severe COPD.
LeMaster William Blake, Witenko Corey J, Lacy Melinda K et al. · Int J Chron Obstruct Pulmon Dis · 2024
PMID: 39429809RCTFull text (PMC)
The Efficacy and Safety of Revefenacin for the Treatment of Chronic Obstructive Pulmonary Disease: A Systematic Review.
Zhang Jiaxing, Xie Yihong, Kwong Joey Sum-Wing et al. · Front Pharmacol · 2021
PMID: 34744701ReviewFull text (PMC)
Quantification and Aerodynamic Particle Size Distribution of Revefenacin Aerosol With UHPLC-MS/MS.
Zhu Difeng, Dou Jing, Ping Li et al. · J Sep Sci · 2025
PMID: 40836375Other
Estimating Tiotropium Wasted Doses After Adding Revefenacin to an Inpatient Formulary: A Single-Center Cross-Sectional Study.
Boylan Paul M, Fuller Jordan A, Guidry Corey M et al. · Hosp Pharm · 2024
PMID: 38764992OtherFull text (PMC)
Population Pharmacokinetics of Revefenacin in Patients with Chronic Obstructive Pulmonary Disease.
Lo Arthur, Borin Marie T, Bourdet David L · Clin Pharmacokinet · 2021
PMID: 33124005OtherFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Revefenacin (substance)
SNOMED CT
782975006
UMLS CUI
C4519232
RxNorm CUI
2102775
Labeler
Viatris Specialty LLC

Clinical Data

This intervention maps to 7 entities in the Ltrl knowledge graph.

1
Conditions
3
Biomarkers
2
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.