Overview
Boxed Warning
FDA Black Box Warning
4.1 5.1 8.1 [see Contraindications (), Warnings and Precautions () and Use in Specific Populations ()]. Do not administer Adempas to a pregnant female because it may cause fetal harm 2.3 5.1 5.2 8.3 [see Dosage and Administration (), Warnings and Precautions (,),and Use in Specific Populations ()].
Indications & Related Conditions
Conditions associated via SNOMED clinical relationships
Administration & Protocol
Dosing, route, and treatment protocol
Detailed dosage and administration information is available in the full FDA drug label.
View full prescribing information on DailyMedMonitoring & Follow-Up
Biomarkers relevant to this intervention via related conditions
No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.
Clinical Trials
6 trials linked to this intervention
Recent Trials
A Long-term Extension Study of Riociguat in Patients With Symptomatic Pulmonary Arterial Hypertension.
Switching of Sildenafil to Riociguat in CTEPH Patients
Pulmonary Hypertension: Intensification and Personalisation of Combination Rx
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy
Measuring Outcomes In Patients With Pulmonary Arterial Hypertension Not on Active Treatment (MOTION)
Research Evidence
Published studies and systematic reviews
Research data from MEDLINE/PubMed
Benefits & Expected Outcomes
Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.
Risks & Side Effects
Adverse reaction and safety data for this drug is sourced from the FDA-approved label.
View adverse reactions & drug interactions on DailyMedRelated Symptoms
Symptoms associated with conditions this intervention addresses
No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.
Alternatives & Comparisons
Alternative treatments, comparison data, and clinical decision support are pending physician authorship.
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Do not start, stop, or change any treatment without consulting your healthcare provider.
Quick Facts
- Type
- Substance / Medication
- Fully Specified Name
- Riociguat (substance)
- SNOMED CT
- 713333001
- UMLS CUI
- C2717561
- RxNorm CUI
- 1439816
- Labeler
- Bayer HealthCare Pharmaceuticals Inc.
Clinical Data
This intervention maps to 1 entities in the Ltrl knowledge graph.
Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.