Substance / Medication

Rituximab

Overview

Active Ingredient
rituximab
RxNorm CUI
121191
Labeler: Genentech, Inc.Updated: 2025-12-15T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

102 trials linked to this intervention

102
Total Trials
59
Recruiting
18
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Nocardiosis in systemic lupus erythematosus patients treated with rituximab: Report of two cases and systematic review of literature.
Gil-Rodríguez Jaime, Fernández Javier de la Hera, Ruiz Michel Martos et al. · Lupus · 2025
PMID: 40013520Meta-Analysis
Rituximab therapy for connective tissue disease-associated interstitial lung disease: a systematic review and meta-analysis.
Zhang Jiaqi, Wan Yanjun, Liu Liheng et al. · Postgrad Med J · 2025
PMID: 40044124Meta-Analysis
Efficacy and safety of rituximab in patients with lupus nephritis: A systematic review and meta-analysis.
Tang Zhiming, Huang Yanqin, Lin Yuqian et al. · Clin Nephrol · 2025
PMID: 39545389Meta-Analysis
Use of rituximab in mature, high-grade and advanced-stage pediatric B-lineage non-Hodgkin lymphomas: a systematic review, meta-analysis and the Brazilian reality.
de Castro Alejandra Adriana Cardoso, de Oliveira Liana Alves, de Andrade Diancarlos Pereira et al. · Front Pediatr · 2025
PMID: 39902063Meta-AnalysisFull text (PMC)
Rituximab Therapy for Adult Refractory Systemic Lupus Erythematosus with Neurological and/or Psychiatric Presentations: A PRISMACompliant Meta-Analysis.
Asad Ayoubi Mehran, Moghaddassi Maryam, Aloosh Mehdi · Curr Rheumatol Rev · 2025
PMID: 39136518Meta-Analysis
Efficacy and safety of rituximab in anti-MuSK myasthenia Gravis: a systematic review and meta-analysis.
Chayanopparat Siripong, Banyatcharoen Perasin, Jitprapaikulsan Jiraporn et al. · Sci Rep · 2025
PMID: 40021769Meta-AnalysisFull text (PMC)
Efficacy of Rituximab in Autoimmune-Mediated IgG4 Pancreaticobiliary Disease: A Systematic Review and Meta-Analysis.
Loganathan Priyadarshini, Siby Ninette, Mohan Babu P et al. · J Clin Gastroenterol · 2025
PMID: 39331507Meta-Analysis
Rituximab Treatment in Adult Patients With Idiopathic Inflammatory Myositis: A Systematic Review and Meta-analysis.
Rojas Lilian Otalora, Ramsubeik Karishma, Sanchez-Ramos Luis et al. · J Clin Rheumatol · 2025
PMID: 39527803Meta-Analysis
Efficacy and safety of polatuzumab-vedotin plus bendamustine and rituximab in patients with relapsed/refractory diffuse large B-cell lymphoma: A systematic review and meta-analysis.
Farooqi Hanzala Ahmed, Saffi Ullah Muhammad, Raza Ahmed et al. · Crit Rev Oncol Hematol · 2025
PMID: 39793679Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Rituximab (substance)
SNOMED CT
386919002
UMLS CUI
C0393022
RxNorm CUI
121191
Labeler
Genentech, Inc.

Clinical Data

This intervention maps to 16 entities in the Ltrl knowledge graph.

6
Conditions
4
Biomarkers
3
Specialists
0
Symptoms
102
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.