Overview
Indications
Adults Clinical Studies (14) [see] Sildenafil for oral suspension is indicated for the treatment of pulmonary arterial hypertension (PAH) (World Health Organization [WHO] Group I) in adults to improve exercise ability and delay clinical worsening. Pediatric use information is approved for Viatris Specialty LLC’s, REVATIO (sildenafil) oral suspension. However, due to Viatris Specialty LLC’s marketing exclusivity rights, this drug product is not labeled with that information.
Contraindications
When this intervention should not be used
Sildenafil for oral suspension is contraindicated in patients with: Warnings and Precautions (5.1) [see] Concomitant use of organic nitrates in any form, either regularly or intermittently, because of the greater risk of hypotension. Concomitant use of riociguat, a guanylate cyclase stimulator. Phos
Indications & Related Conditions
Conditions associated via SNOMED clinical relationships
Administration & Protocol
Dosing, route, and treatment protocol
Detailed dosage and administration information is available in the full FDA drug label.
View full prescribing information on DailyMedMonitoring & Follow-Up
Biomarkers relevant to this intervention via related conditions
No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.
Clinical Trials
55 trials linked to this intervention
Recent Trials
Phase IV Study of Chronic Infusional Epoprostenol for Severe Primary Pulmonary Hypertension
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
A Transition Study From Flolan® to Remodulin® in Patients With Pulmonary Arterial Hypertension
Natural History of Sickle Cell Disease
The Effect of Tracleer® on Male Fertility
Research Evidence
Published studies and systematic reviews
Research data from MEDLINE/PubMed
Benefits & Expected Outcomes
Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.
Risks & Side Effects
Adverse reaction and safety data for this drug is sourced from the FDA-approved label.
View adverse reactions & drug interactions on DailyMedRelated Symptoms
Symptoms associated with conditions this intervention addresses
No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.
Alternatives & Comparisons
Alternative treatments, comparison data, and clinical decision support are pending physician authorship.
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Do not start, stop, or change any treatment without consulting your healthcare provider.
Quick Facts
- Type
- Substance / Medication
- Fully Specified Name
- Sildenafil (substance)
- SNOMED CT
- 372572000
- UMLS CUI
- C0529793
- RxNorm CUI
- 136411
- Labeler
- Amneal Pharmaceuticals NY LLC
Clinical Data
This intervention maps to 1 entities in the Ltrl knowledge graph.
Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.