Substance / Medication

Sodium bicarbonate

Overview

Active Ingredient
sodium bicarbonate
RxNorm CUI
36676

Indications

Omeprazole and sodium bicarbonate capsules are indicated in adults for the : short-term treatment of active duodenal ulcer. Most patients heal within four weeks. Some patients may require an additional four weeks of therapy. short-term treatment (4 to 8 weeks) of active benign gastric ulcer. treatment of heartburn and other symptoms associated with GERD for up to 4 weeks. The efficacy of omeprazole and sodium bicarbonate used for longer than 8 weeks in patients with EE has not been established.

Labeler: Westminster Pharmaceuticals, LLCUpdated: 2026-02-13T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Warnings and Precautions (5.2) Adverse Reactions (6.2) [see,]. Omeprazole and sodium bicarbonate is contraindicated in patients with known hypersensitivity to substituted benzimidazoles or to any component of the formulation. Hypersensitivity reactions may include anaphylaxis, anaphylactic shock, an

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Sodium bicarbonate Ringer's solution for hemorrhagic shock: A meta-analysis comparing crystalloid solutions.
Shafique Muhammad Ashir, Shaikh Noman Adil, Haseeb Abdul et al. · Am J Emerg Med · 2024
PMID: 37988980Meta-Analysis
Sodium Bicarbonate Treatment and Clinical Outcomes in Chronic Kidney Disease with Metabolic Acidosis: A Meta-Analysis.
Yang Ting-Ya, Lin Hong-Min, Wang Hsien-Yi et al. · Clin J Am Soc Nephrol · 2024
PMID: 38980732Meta-AnalysisFull text (PMC)
Effect of β-alanine and sodium bicarbonate co-supplementation on the body's buffering capacity and sports performance: A systematic review.
Gilsanz Laura, López-Seoane Jaime, Jiménez Sergio L et al. · Crit Rev Food Sci Nutr · 2023
PMID: 34882489Meta-Analysis
Prevention and the treatment of oral mucositis: the efficacy of sodium bicarbonate vs other agents: a systematic review.
Di Fede O, Canepa F, Maniscalco L et al. · BMC Oral Health · 2023
PMID: 36597048Meta-AnalysisFull text (PMC)
Effect of Sodium Bicarbonate on Systolic Blood Pressure in CKD: A Systematic Review and Meta-Analysis.
Beynon-Cobb Beverley, Louca Panayiotis, Hoorn Ewout J et al. · Clin J Am Soc Nephrol · 2023
PMID: 36758154Meta-AnalysisFull text (PMC)
Acute effects of sodium bicarbonate ingestion on cycling time-trial performance: A systematic review and meta-analysis of randomized controlled trials.
Lopes-Silva João Paulo, Correia-Oliveira Carlos Rafaell · Eur J Sport Sci · 2023
PMID: 35633035Meta-Analysis
The effect of sodium bicarbonate on OHCA patients: A systematic review and meta-analysis of RCT and propensity score studies.
Xu Tingzhen, Wu Chenxia, Shen Qinkang et al. · Am J Emerg Med · 2023
PMID: 37611525Meta-Analysis
EFFICACY OF 67% SODIUM BICARBONATE TOOTHPASTE FOR PLAQUE AND GINGIVITIS CONTROL: A SYSTEMATIC REVIEW AND META-ANALYSIS.
Taschieri Silvio, Tumedei Margherita, Francetti Luca et al. · J Evid Based Dent Pract · 2022
PMID: 35718441Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium bicarbonate (substance)
SNOMED CT
387319002
UMLS CUI
C0074722
RxNorm CUI
36676
Labeler
Westminster Pharmaceuticals, LLC

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.