Substance / Medication

Sodium chloride

Overview

Active Ingredient
sodium chloride
RxNorm CUI
9863

Indications

Dosage and Administration (2) [See.] Use only with Trima Accel red blood cell (RBC) apheresis collections.

Labeler: Terumo BCT, LtdUpdated: 2026-01-30T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

DO NOT INFUSE ADDITIVE SOLUTION FORMULA 3 (AS-3) DIRECTLY TO THE DONOR.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

574 trials linked to this intervention

574
Total Trials
99
Recruiting
131
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Sodium Chloride versus Lactose as a Carrier for House Dust Mite Allergen in Allergen Chamber Studies: A Clinical Study to Assess Noninferiority.
Struß Nadja, Dieter Susanne, Schwarz Katharina et al. · Int Arch Allergy Immunol · 2023
PMID: 37586347Meta-Analysis
Reduction of sodium chloride: a review.
Shen Dongyu, Song Huanlu, Zou Tingting et al. · J Sci Food Agric · 2022
PMID: 35266156Meta-Analysis
Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults.
López-Briz Eduardo, Ruiz Garcia Vicente, Cabello Juan B et al. · Cochrane Database Syst Rev · 2022
PMID: 35849083Meta-AnalysisFull text (PMC)
Is Epidural Injection of Sodium Chloride Solution a True Placebo or an Active Control Agent? A Systematic Review and Meta-Analysis.
Manchikanti Laxmaiah, Knezevic Nebojsa Nick, Sanapati Jaya et al. · Pain Physician · 2021
PMID: 33400427Meta-Analysis
Heparin versus 0.9% sodium chloride locking for prevention of occlusion in central venous catheters in adults.
López-Briz Eduardo, Ruiz Garcia Vicente, Cabello Juan B et al. · Cochrane Database Syst Rev · 2018
PMID: 30058070Meta-AnalysisFull text (PMC)
Meta-Analysis of Individual Patient Data of Sodium Bicarbonate and Sodium Chloride for All-Cause Mortality After Coronary Angiography.
Brown Jeremiah R, Pearlman Daniel M, Marshall Emily J et al. · Am J Cardiol · 2016
PMID: 27642111Meta-AnalysisFull text (PMC)
Heparin versus 0.9% sodium chloride intermittent flushing for the prevention of occlusion in long term central venous catheters in infants and children.
Bradford Natalie K, Edwards Rachel M, Chan Raymond J · Cochrane Database Syst Rev · 2015
PMID: 26590504Meta-Analysis
Heparin versus 0.9% sodium chloride intermittent flushing for prevention of occlusion in central venous catheters in adults.
López-Briz Eduardo, Ruiz Garcia Vicente, Cabello Juan B et al. · Cochrane Database Syst Rev · 2014
PMID: 25300172Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium chloride (substance)
SNOMED CT
387390002
UMLS CUI
C0037494
RxNorm CUI
9863
Labeler
Terumo BCT, Ltd

Clinical Data

This intervention maps to 3 entities in the Ltrl knowledge graph.

3
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
574
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.