Substance / Medication

Sodium thiosulfate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Influence of sodium thiosulfate on coronary artery calcification of patients on dialysis: a meta-analysis.
Huang Chong, Duan Zhibing, Xu Chengyun et al. · Ren Fail · 2023
PMID: 37755153Meta-AnalysisFull text (PMC)
Sodium Thiosulfate for Calciphylaxis Treatment in Patients on Peritoneal Dialysis: A Systematic Review.
Gossett Christy, Suppadungsuk Supawadee, Krisanapan Pajaree et al. · Medicina (Kaunas) · 2023
PMID: 37512116Meta-AnalysisFull text (PMC)
Topical sodium thiosulfate as treatment of calcinosis cutis: Case series and systematic review.
Ricardo Jose W, Sun Helen Y, Gorji Mahdieh et al. · J Am Acad Dermatol · 2022
PMID: 34537249Meta-Analysis
Association of Sodium Thiosulfate With Risk of Ototoxic Effects From Platinum-Based Chemotherapy: A Systematic Review and Meta-analysis.
Chen Chih-Hao, Huang Chii-Yuan, Lin Heng-Yu Haley et al. · JAMA Netw Open · 2021
PMID: 34338793Meta-AnalysisFull text (PMC)
Systematic review of sodium thiosulfate in treating calciphylaxis in chronic kidney disease patients.
Peng Ting, Zhuo Ling, Wang Ying et al. · Nephrology (Carlton) · 2018
PMID: 28603903Meta-Analysis
Otoprotective Effects of Sodium Thiosulfate by Demographic and Clinical Characteristics: A Report From Children's Oncology Group Study ACCL0431.
Ohlsen Timothy J D, Collier Willem H, Ramdas Jagadeesh et al. · Pediatr Blood Cancer · 2025
PMID: 39654065RCTFull text (PMC)
Effects of sodium thiosulfate on serum calcification factors in patients undergoing maintenance hemodialysis.
Liu Pan, Xu Xiang, Wang YuFu et al. · Ther Apher Dial · 2023
PMID: 37424269RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Sodium thiosulfate (substance)
SNOMED CT
387209006
UMLS CUI
C0074774

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.