Substance / Medication

Tazarotene

Overview

Active Ingredient
tazarotene
RxNorm CUI
83947

Indications

® FABIOR(tazarotene) Foam, 0.1% is indicated for the topical treatment of acne vulgaris in patients 12 years of age or older.

Labeler: Mayne PharmaUpdated: 2026-02-16T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

FABIOR Foam is contraindicated in pregnancy. FABIOR Foam may cause fetal harm when administered to a pregnant woman. Use in Specific Populations (8.1) [see]. Tazarotene elicits teratogenic and developmental effects associated with retinoids after topical or systemic administration in rats and rabbit

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

240 trials linked to this intervention

240
Total Trials
29
Recruiting
125
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Treating Psoriasis With Halobetasol Propionate and Tazarotene Combination: A Review of Phase II and III Clinical Trials.
Ramachandran Vignesh, Bertus Brooke, Bashyam Arjun M et al. · Ann Pharmacother · 2020
PMID: 32126800Meta-Analysis
Tazarotene is as effective and well-tolerated as imiquimod in the treatment of verruca plana: a comparative randomized controlled trial.
Nofal Hagar, Omran Fatma, ElKholy Basma et al. · Clin Exp Dermatol · 2024
PMID: 38618753RCT
Improvements in acne and skin oiliness with tazarotene 0.045% lotion in patients with oily skin.
Tanghetti Emil A, Zeichner Joshua A, Gold Michael et al. · J Dermatolog Treat · 2023
PMID: 36382987RCT
Efficacy and Safety of Tazarotene 0.045% Lotion in Caucasian Adults With Moderate-to-Severe Acne.
Del Rosso James, Stein Gold Linda, Tyring Stephen et al. · J Drugs Dermatol · 2022
PMID: 36219057RCT
Tazarotene 0.045% Lotion for Females With Acne: Analysis of Two Adult Age Groups.
Stein Gold Linda, Kircik Leon, Baldwin Hilary et al. · J Drugs Dermatol · 2022
PMID: 35674760RCT
Dermal sensitization, safety, tolerability, and patient preference of tazarotene 0.045% lotion from five clinical trials.
Kircik Leon H, Green Lawrence, Guenin Eric et al. · J Dermatolog Treat · 2022
PMID: 34459694RCT
Efficacy of combined fractional carbon dioxide laser and topical tazarotene in nail psoriasis treatment: A randomized intrapatient left-to-right study.
Essa Abd Elazim Nagwa, Mahmoud Abdelsalam Ayat, Mohamed Awad Sara · J Cosmet Dermatol · 2022
PMID: 34664357RCT
Once-Daily Polymeric Tazarotene 0.045% Lotion for Moderate-to-Severe Acne: Pooled Phase 3 Analysis by Sex.
Kircik Leon H., Gold Linda Stein, Beer Kenneth et al. · J Drugs Dermatol · 2020
PMID: 32845584RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tazarotene (substance)
SNOMED CT
386935009
UMLS CUI
C0288792
RxNorm CUI
83947
Labeler
Mayne Pharma

Clinical Data

This intervention maps to 2 entities in the Ltrl knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
240
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.