Substance / Medication

Tiagabine

Overview

Active Ingredient
tiagabine
RxNorm CUI
31914

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

2 trials linked to this intervention

2
Total Trials
0
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Tiagabine add-on for drug-resistant partial epilepsy.
Pulman Jennifer, Hutton Jane L, Marson Anthony G · Cochrane Database Syst Rev · 2014
PMID: 24500879Meta-AnalysisFull text (PMC)
Tiagabine for acute affective episodes in bipolar disorder.
Vasudev Akshya, Macritchie Karine, Rao Sanjay K et al. · Cochrane Database Syst Rev · 2012
PMID: 23235614Meta-AnalysisFull text (PMC)
Tiagabine add-on for drug-resistant partial epilepsy.
Pulman Jennifer, Marson Anthony G, Hutton Jane L · Cochrane Database Syst Rev · 2012
PMID: 22592677Meta-AnalysisFull text (PMC)
Tiagabine in the maintenance treatment of bipolar disorder.
Vasudev Akshya, Macritchie Karine, Rao Sanjay Nk et al. · Cochrane Database Syst Rev · 2011
PMID: 22161389Meta-AnalysisFull text (PMC)
Tiagabine in the treatment of acute affective episodes in bipolar disorder: efficacy and acceptability.
Young A H, Geddes J R, Macritchie K et al. · Cochrane Database Syst Rev · 2006
PMID: 16856056Meta-Analysis
Tiagabine in the maintenance treatment of bipolar disorders.
Young A H, Geddes J R, Macritchie K et al. · Cochrane Database Syst Rev · 2006
PMID: 16856081Meta-Analysis
Tiagabine add-on for drug-resistant partial epilepsy.
Pereira J, Marson A G, Hutton J L · Cochrane Database Syst Rev · 2002
PMID: 12137637Meta-Analysis
Influence of tiagabine maintenance on cannabis effects and related behaviors in daily cannabis users.
Wesley Michael J, Westgate Philip M, Stoops William W et al. · Exp Clin Psychopharmacol · 2018
PMID: 29863387RCTFull text (PMC)
Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea.
Taranto-Montemurro Luigi, Sands Scott A, Edwards Bradley A et al. · Sleep · 2017
PMID: 28364504RCTFull text (PMC)
Slow wave sleep induced by GABA agonist tiagabine fails to benefit memory consolidation.
Feld Gordon B, Wilhelm Ines, Ma Ying et al. · Sleep · 2013
PMID: 23997364RCTFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Specialists

Providers who commonly manage this intervention

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Tiagabine (substance)
SNOMED CT
372485004
UMLS CUI
C0068897
RxNorm CUI
31914

Clinical Data

This intervention maps to 9 entities in the Ltrl knowledge graph.

4
Conditions
3
Biomarkers
1
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.