Substance / Medication

Treprostinil sodium

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

55 trials linked to this intervention

55
Total Trials
13
Recruiting
16
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Stability and antimicrobial effectiveness of treprostinil sodium in Sterile Diluent for Flolan.
Zaccardelli D, Phares K, Jeffs R et al. · Int J Clin Pract · 2010
PMID: 20584221Observational
Treatment of a nonhealing saphenous vein harvest graft with treprostinil sodium.
Zwicke Dianne, Buggy Brian, Lobacz Don et al. · Ann Thorac Surg · 2008
PMID: 18355483Case Report
Inhaled treprostinil sodium for the treatment of pulmonary arterial hypertension.
Ferrantino Matthew, White R James · Expert Opin Pharmacother · 2011
PMID: 21988216Review
Overview of treprostinil sodium for the treatment of pulmonary arterial hypertension.
Budev Marie M, Minai Omar A, Arroliga Alejandro C · Drugs Today (Barc) · 2004
PMID: 15148531Review
Compatibility of treprostinil sodium and dopamine hydrochloride during simulated Y-site administration.
Bustin Anna, Ramsey E Zachary, Hanna Brian D et al. · Am J Health Syst Pharm · 2020
PMID: 32236454Other
Pharmacokinetics of treprostinil sodium administered by 28-day chronic continuous subcutaneous infusion.
Wade Michael, Baker F Jo, Roscigno Robert et al. · J Clin Pharmacol · 2004
PMID: 15102871Other
Dose proportionality of treprostinil sodium administered by continuous subcutaneous and intravenous infusion.
McSwain C Shane, Benza Ray, Shapiro Shelley et al. · J Clin Pharmacol · 2008
PMID: 18094217Trial
Efficacy of long-term subcutaneous treprostinil sodium therapy in pulmonary hypertension.
Lang Irene, Gomez-Sanchez Miguel, Kneussl Meinhard et al. · Chest · 2006
PMID: 16778286Trial
Absolute bioavailability and pharmacokinetics of treprostinil sodium administered by acute subcutaneous infusion.
Wade Michael, Baker F Jo, Roscigno Robert et al. · J Clin Pharmacol · 2004
PMID: 14681345Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Treprostinil sodium (substance)
SNOMED CT
385681001
UMLS CUI
C1144481

Clinical Data

This intervention maps to 1 entities in the Ltrl knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
55
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.