Substance / Medication

Voriconazole

Overview

Active Ingredient
voriconazole
RxNorm CUI
121243
Labeler: RoerigUpdated: 2026-02-09T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

• Warnings and Precautions (5.5) Adverse Reactions (6.1, 6.2) [seeand] VFEND is contraindicated in patients with known hypersensitivity to voriconazole or its excipients. There is no information regarding cross-sensitivity between VFEND and other azole antifungal agents. Refer to the prescribing inf

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

16 trials linked to this intervention

16
Total Trials
0
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
variability and clinical outcomes of clopidogrel, proton pump inhibitors, and voriconazole in Southeast Asia: a systematic review and meta-analysis.
Hardi Harri, Barinda Agian Jeffilano, Mahata Liganda Endo et al. · Front Pharmacol · 2025
PMID: 40612749Meta-AnalysisFull text (PMC)
Factors affecting voriconazole pharmacokinetic variability in critically ill patients: a systematic review.
Coste Anne, Aubron Cécile, Ansart Séverine et al. · Crit Care · 2025
PMID: 41291870Meta-AnalysisFull text (PMC)
Clinical application of voriconazole in pediatric patients: a systematic review.
Hu Lin, Huang Juanjuan, Li Yanfei et al. · Ital J Pediatr · 2024
PMID: 38853280Meta-AnalysisFull text (PMC)
Associated factors with voriconazole plasma concentration: a systematic review and meta-analysis.
Li Xiaoqi, Hu Qiaozhi, Xu Ting · Front Pharmacol · 2024
PMID: 39246651Meta-AnalysisFull text (PMC)
Breakthrough Invasive Fungal Infections in Patients With High-Risk Hematological Disorders Receiving Voriconazole and Posaconazole Prophylaxis: A Systematic Review.
Boutin Catherine-Audrey, Durocher Florence, Beauchemin Stéphanie et al. · Clin Infect Dis · 2024
PMID: 38752732Meta-AnalysisFull text (PMC)
Effects of inflammation on voriconazole levels: A systematic review.
Li Xuejuan, Lai Fangyuan, Jiang Zhaohui et al. · Br J Clin Pharmacol · 2022
PMID: 35973037Meta-Analysis
Impact of cytochrome P450 2C19 polymorphisms on the clinical efficacy and safety of voriconazole: an update systematic review and meta-analysis.
Zhang Ying, Hao Xu, Hou Kelu et al. · Pharmacogenet Genomics · 2022
PMID: 35947050Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Voriconazole (substance)
SNOMED CT
385469007
UMLS CUI
C0393080
RxNorm CUI
121243
Labeler
Roerig

Clinical Data

This intervention maps to 4 entities in the Ltrl knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
16
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.