Substance / Medication

AbobotulinumtoxinA

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

13 trials linked to this intervention

13
Total Trials
2
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
AbobotulinumtoxinA Doses in Upper and Lower Limb Spasticity: A Systematic Literature Review.
Schnitzler Alexis, Dince Clément, Freitag Andreas et al. · Toxins (Basel) · 2022
PMID: 36355984Meta-AnalysisFull text (PMC)
Use of AbobotulinumtoxinA for Cosmetic Treatments in the Neck, and Middle and Lower Areas of the Face: A Systematic Review.
Galadari Hassan, Galadari Ibrahim, Smit Riekie et al. · Toxins (Basel) · 2021
PMID: 33671800Meta-AnalysisFull text (PMC)
Treatment approaches and outcomes associated with the use of abobotulinumtoxinA for the treatment of hyperhidrosis: A systematic review.
Galadari Hassan, Galadari Ibrahim, Smit Riekie et al. · J Am Acad Dermatol · 2021
PMID: 32781184Meta-Analysis
Use of AbobotulinumtoxinA in Adults with Cervical Dystonia: A Systematic Literature Review.
Fasano Alfonso, Paramanandam Vijayashankar, Jog Mandar · Toxins (Basel) · 2020
PMID: 32722133Meta-AnalysisFull text (PMC)
Safety and Patient Satisfaction of AbobotulinumtoxinA for Aesthetic Use: A Systematic Review.
Cohen Joel L, Scuderi Nicolo · Aesthet Surg J · 2017
PMID: 28388721Meta-AnalysisFull text (PMC)
Systematic Literature Review of AbobotulinumtoxinA in Clinical Trials for Lower Limb Spasticity.
Dashtipour Khashayar, Chen Jack J, Walker Heather W et al. · Medicine (Baltimore) · 2016
PMID: 26765447Meta-AnalysisFull text (PMC)
Systematic literature review of abobotulinumtoxinA in clinical trials for adult upper limb spasticity.
Dashtipour Khashayar, Chen Jack J, Walker Heather W et al. · Am J Phys Med Rehabil · 2015
PMID: 25299523Meta-AnalysisFull text (PMC)
AbobotulinumtoxinA for reduction of glabellar lines in patients with skin of color: post hoc analysis of pooled clinical trial data.
Taylor Susan C, Callender Valerie D, Albright Craig D et al. · Dermatol Surg · 2012
PMID: 22928999Meta-Analysis
Current aesthetic use of abobotulinumtoxinA in clinical practice: an evidence-based consensus review.
Maas Corey, Kane Michael A C, Bucay Vivian W et al. · Aesthet Surg J · 2012
PMID: 22941910Meta-Analysis
Contemporary management of lower urinary tract disease with botulinum toxin A: a systematic review of botox (onabotulinumtoxinA) and dysport (abobotulinumtoxinA).
Mangera Altaf, Andersson Karl-Erik, Apostolidis Apostolos et al. · Eur Urol · 2011
PMID: 21782318Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
AbobotulinumtoxinA (substance)
SNOMED CT
444619001
UMLS CUI
C2719424

Clinical Data

This intervention maps to 5 entities in the Ltrl knowledge graph.

5
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
13
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.