Substance / Medication

Benzocaine

Overview

Active Ingredient
benzocaine
RxNorm CUI
1399

Indications

Únicamente para ser usado en la mucosa oral, según indicacionesdel dentista. Para el alivio temporal del dolor debido a procedimientos dentales menores.

Labeler: Mycone Dental Supply Co., Inc DBA Keystone Industries and Deepak Products Inc.Updated: 2025-11-13T00:00:00.000ZFull label on DailyMed

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

19 trials linked to this intervention

19
Total Trials
4
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Comparing the Efficacy of a Compound Topical Anesthetic Versus Benzocaine: A Pilot Study.
Park Lydia, Tom James, Bui Nicole et al. · Anesth Prog · 2020
PMID: 32191506RCTFull text (PMC)
Efficacy of Topical Benzocaine in Maxilla: A Randomized Controlled Trial.
Rehman Nurain, Qazi Samir Riaz · Anesth Prog · 2019
PMID: 30883233RCTFull text (PMC)
Lack of Methemoglobin Elevations After Topical Applications of Benzocaine Alone or Benzocaine Plus Tetracaine to the Oral Mucosa.
Wang Steven, Giannakopoulos Helen, Lowstetter Jamie et al. · Clin Ther · 2017
PMID: 28943117RCT
Effect of 5% benzocaine gel on relieving pain caused by fixed orthodontic appliance activation. A double-blind randomized controlled trial.
Eslamian L, Gholami H, Mortazavi S A R et al. · Orthod Craniofac Res · 2016
PMID: 27659276RCT
Randomized controlled trial of benzocaine versus placebo spray for pain relief at hysterosalpingogram.
Bachman E A, Senapati S, Sammel M D et al. · Reprod Biomed Online · 2014
PMID: 24745839RCTFull text (PMC)
Using topical benzocaine before lingual frenotomy did not reduce crying and should be discouraged.
Ovental A, Marom R, Botzer E et al. · Acta Paediatr · 2014
PMID: 24724835RCT
Role of duodenal mucosal nerve endings in the acid-induced duodenogastric sensorimotor reflex: effect of benzocaine in healthy humans.
Vanuytsel T, Karamanolis G, Vos R et al. · Neurogastroenterol Motil · 2013
PMID: 23565580RCT
The effect of clove and benzocaine versus placebo as topical anesthetics.
Alqareer Athbi, Alyahya Asma, Andersson Lars · J Dent · 2006
PMID: 16530911RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Benzocaine (substance)
SNOMED CT
387357002
UMLS CUI
C0005059
RxNorm CUI
1399
Labeler
Mycone Dental Supply Co., Inc DBA Keystone Industries and Deepak Products Inc.

Clinical Data

This intervention maps to 6 entities in the Ltrl knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
19
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Ltrl clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.