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Autosomal dominant hereditary spastic paraplegia

disorder

SNOMED 737227004CUI C0751602

Overview

Autosomal dominant hereditary spastic paraplegia is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Distal limb muscle weakness due to peripheral neuropathy

Always present (100%)HP:0002460

Involuntary muscle stiffness, contraction, or spasm

Occasional (5-29%)HP:0001257

Cavus foot

HP:0001761

Corticospinal signs

HP:0007256

Decreased motor nerve conduction velocity

HP:0003431

Distal muscle atrophy, upper and lower limbs

HP:0003693

Dysphonia

HP:0001618

Extensor plantar responses

HP:0003487

Frequent falls

HP:0002359

Gait disturbance

HP:0001288

Hammertoe

HP:0001765

Inability to heel walk

HP:0009027

Limb muscle weakness

HP:0003690

Loss of distal sensation

HP:0002936

Lower limb pain

HP:0012514

Peripheral axonal neuropathy

HP:0003477

Sensory neuropathy

HP:0000763

Spasticity and rigidity of muscles

HP:0001276

Related Conditions

Autosomal dominant spastic paraplegia type 4(child)

Autosomal dominant spastic paraplegia type 10(child)

Autosomal dominant familial spastic paraplegia type 3(child)

Autosomal dominant spastic paraplegia type 31(child)

Autosomal dominant spastic paraplegia type 41(child)

Autosomal dominant spastic paraplegia type 42(child)

Autosomal dominant spastic paraplegia type 12(child)

Autosomal dominant spastic paraplegia type 19(child)

Autosomal dominant spastic paraplegia type 3(child)

Autosomal dominant spastic paraplegia type 13(child)

Autosomal dominant spastic paraplegia type 8(child)

Autosomal dominant spastic paraplegia type 37(child)

Autosomal dominant spastic paraplegia type 9B(child)

Autosomal dominant spastic paraplegia type 73(child)

Autosomal dominant complex hereditary spastic paraplegia(child)

Autosomal dominant hereditary disorder(parent)

Hereditary spastic paraplegia(parent)

Quick Facts

SNOMED CT: 737227004
UMLS CUI: C0751602
Fully Specified Name: Autosomal dominant hereditary spastic paraplegia (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 18

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.